--- title: "Supplement of the week: Designs for Health 5-HTP Synergy" description: 5-HTP Synergy™ is a synergistic formula of 5-hydroxytryptophan (50 mg) and vitamin B6 (10 mg) for supporting overall neurotransmitter image: https://blog.primohealth.com/hs-fs/file-1601696438-jpg/images/htp090-lrg_1.jpg --- [![Primo Health - Daniel Sanelli](https://blog.primohealth.com/hs-fs/hubfs/PHC_LogoCR_HUBSPOT.png?width=400&height=154&name=PHC_LogoCR_HUBSPOT.png "Primo Health - Daniel Sanelli")](https://www.primohealth.com) - [About](https://www.primohealth.com/about-daniel-sanelli) - [Program](https://www.primohealth.com/functional-blood-chemistry-analysis) - [Store](https://www.primohealth.com/primo-health-store) - [How to Shop](https://www.primohealth.com/primo-health-store) - [Primo Health Store](https://primohealthcoach.gethealthy.store) - [FullScript Dispensary](https://us.fullscript.com//welcome/primohealth) - [Apex Energetics Store](https://www.myhcpstore.com/) - [Blog](https://blog.primohealth.com) - [Contact](https://www.primohealth.com/contact-daniel-sanelli) [Back to blog](https://blog.primohealth.com) # Supplement of the week: Designs for Health 5-HTP Synergy ![Picture of Daniel Sanelli, M.Sc.](https://app.hubspot.com/settings/avatar/18cc72d6b6902b69f00313c2a3004f25) [Daniel Sanelli, M.Sc.](https://blog.primohealth.com/author/daniel-sanelli-m-sc) Sep 10, 2014 5:10:00 PM [brain health](https://blog.primohealth.com/topic/brain-health) [smart supplementation](https://blog.primohealth.com/topic/smart-supplementation) ## ![htp090 lrg 1](https://blog.primohealth.com/hs-fs/file-1601696438-jpg/images/htp090-lrg_1.jpg)**Quick Overview** 5-HTP Synergy™ is a synergistic formula of 5-hydroxytryptophan (50 mg) and vitamin B6 (10 mg) for supporting overall neurotransmitter metabolism by providing precursors of serotonin. 5-HTP readily enters the blood brain barrier, however conversion into serotonin requires the cofactor vitamin B6, which is included in this formula. 5-HTP Synergy™ may be used during the day to support healthy mood or appetite or at bedtime to support sleep. ## **Product Description** Our modern, stressful lives lower levels of the feel-good neurotransmitter serotonin. Serotonin depletion leads to food cravings, depression, and other mood disorders. The pharmaceutical industry has responded to the serotonin crisis by creating a wide array of medications which seek to restore serotonin metabolism. A better approach may be to replete serotonin naturally by using its precursor, 5-hydroxytryptophan (5HTP). Naturally restoring serotonin levels may help promote healthy mood levels and may also reduce food cravings.\* Pyridoxal-5-Phosphate (P5P), the activated form of vitamin B6, is included in this formula to support overall neurotransmitter metabolism. ## **Ingredients** Vitamin B6 (Pyridoxal-5-Phosphate) 10 mg; 5-HTP (5-Hydroxytryptophan) 50 mg. ## **Dosage** As a dietary supplement, take one capsule per day or as directed by your health care practitioner. ## **Caution** Not recommended for use by pregnant or lactating women, or if you are taking SSRIs or MAO inhibitors. 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